About The Medical Condition MPTP Poisoning
Find the definition of the medical term MPTP Poisoning. MPTP Poisoning defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
MPTP Poisoning
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What's The Definition Of The Medical Condition MPTP Poisoning?
A condition caused by the neurotoxin 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. MPTP causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)
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