About The Medical Condition Mu-Chain Diseases

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Find the definition of the medical term Mu-Chain Diseases. Mu-Chain Diseases defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Mu-Chain Diseases

Mu-Chain Diseases Medical Condition Defined & Explained
Mu-Chain Diseases Medical Condition

What's The Definition Of The Medical Condition Mu-Chain Diseases?

A disorder of immunoglobulin synthesis in which large quantities of abnormal heavy chains are excreted in the urine. The amino acid sequences of the N-(amino-) terminal regions of these chains are normal, but they have a deletion extending from part of the variable domain through the first domain of the constant region, so that they cannot form cross-links to the light chains. The defect arises through faulty coupling of the variable (V) and constant (C) region genes.

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