About The Medical Condition Myasthenia, Experimental
Find the definition of the medical term Myasthenia, Experimental. Myasthenia, Experimental defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Myasthenia, Experimental
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What's The Definition Of The Medical Condition Myasthenia, Experimental?
Any autoimmune animal disease model used in the study of MYASTHENIA GRAVIS. Injection with purified neuromuscular junction acetylcholine receptor (AChR) (see RECEPTORS, CHOLINERGIC) components results in a myasthenic syndrome that has acute and chronic phases. The motor endplate pathology, loss of acetylcholine receptors, presence of circulating anti-AChR antibodies, and electrophysiologic changes make this condition virtually identical to human myasthenia gravis. Passive transfer of AChR antibodies or lymphocytes from afflicted animals to normals induces passive transfer experimental autoimmune myasthenia gravis. (From Joynt, Clinical Neurology, 1997, Ch 54, p3)
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