About The Medical Condition Myasthenia Gravis, Generalized
Find the definition of the medical term Myasthenia Gravis, Generalized. Myasthenia Gravis, Generalized defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Myasthenia Gravis, Generalized
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What's The Definition Of The Medical Condition Myasthenia Gravis, Generalized?
A disorder of neuromuscular transmission characterized by weakness of cranial and skeletal muscles. Autoantibodies directed against acetylcholine receptors damage the motor endplate portion of the NEUROMUSCULAR JUNCTION, impairing the transmission of impulses to skeletal muscles. Clinical manifestations may include diplopia, ptosis, and weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles. THYMOMA is commonly associated with this condition. (Adams et al., Principles of Neurology, 6th ed, p1459)
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