About The Medical Condition Myb Oncogene
Find the definition of the medical term Myb Oncogene. Myb Oncogene defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Myb Oncogene
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What's The Definition Of The Medical Condition Myb Oncogene?
Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).
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