About The Medical Condition NADP-ADPRTase
Find the definition of the medical term NADP-ADPRTase. NADP-ADPRTase defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
NADP-ADPRTase
| NADP-ADPRTase Medical Condition |
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What's The Definition Of The Medical Condition NADP-ADPRTase?
An enzyme that catalyzes the transfer of the ADP-ribose moiety from NAD to specific protein substrates with agmatine, arginine-type compounds, or guanidine as acceptors. This reaction can be catalyzed by prokaryotic and eukaryotic enzyme systems. Mono-ADP-ribosylation is a mechanism of action common to several bacterial toxins. It effects profound changes in cellular metabolism, such as activation of adenylate cyclase, regulation of protein synthesis at the level of elongation factor 2, and ion transport across biological membranes. EC 2.4.2.31.
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