About The Medical Condition Negative Staining

Find the definition of the medical term Negative Staining. Negative Staining defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Negative Staining

Negative Staining Medical Condition |
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What's The Definition Of The Medical Condition Negative Staining?
The technique of washing tissue specimens with a concentrated solution of a heavy metal salt and letting it dry. The specimen will be covered with a very thin layer of the metal salt, being excluded in areas where an adsorbed macromolecule is present. The macromolecules allow electrons from the beam of an electron microscope to pass much more readily than the heavy metal; thus, a reversed or negative image of the molecule is created.
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