About The Medical Condition Neurofibrosarcoma
Find the definition of the medical term Neurofibrosarcoma. Neurofibrosarcoma defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Neurofibrosarcoma
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What's The Definition Of The Medical Condition Neurofibrosarcoma?
A malignant tumor that arises from small cutaneous nerves, is locally aggressive, and has a potential for metastasis. Characteristic histopathologic features include proliferating atypical spindle cells with slender wavy and pointed nuclei, hypocellular areas, and areas featuring organized whorls of fibroblastic proliferation. The most common primary sites are the extremities, retroperitoneum, and trunk. These tumors tend to present in childhood, often in association with NEUROFIBROMATOSIS 1. (From DeVita et al., Cancer: Principles & Practice of Oncology, 5th ed, p1662; Mayo Clin Proc 1990 Feb;65(2):164-72)
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