About The Medical Condition Nick-End Labelling, In Situ

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Find the definition of the medical term Nick-End Labelling, In Situ. Nick-End Labelling, In Situ defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Nick-End Labelling, In Situ

Nick-End Labelling, In Situ Medical Condition Defined & Explained
Nick-End Labelling, In Situ Medical Condition

What's The Definition Of The Medical Condition Nick-End Labelling, In Situ?

An in situ method for detecting areas of DNA which are nicked during apoptosis. Terminal deoxynucleotidyl transferase is used to add labeled dUTP, in a template-independent manner, to the 3 prime OH ends of either single- or double-stranded DNA. The terminal deoxynucleotidyl transferase nick end labeling, or TUNEL, assay labels apoptosis on a single-cell level, making it more sensitive than agarose gel electrophoresis for analysis of DNA fragmentation.

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