About The Medical Condition Non-Steroidal Antirheumatic Agents
Find the definition of the medical term Non-Steroidal Antirheumatic Agents. Non-Steroidal Antirheumatic Agents defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Non-Steroidal Antirheumatic Agents
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What's The Definition Of The Medical Condition Non-Steroidal Antirheumatic Agents?
Anti-inflammatory agents that are not steroids. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They are used primarily in the treatment of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. Certain NSAIDs also may inhibit lipoxygenase enzymes or phospholipase C or may modulate T-cell function. (AMA Drug Evaluations Annual, 1994, p 1814-5)
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