About The Medical Condition NSC-141540
Find the definition of the medical term NSC-141540. NSC-141540 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
NSC-141540
| NSC-141540 Medical Condition |
|---|
What's The Definition Of The Medical Condition NSC-141540?
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Skeletin ‐ An intermediate filament protein found predominantly in smooth,…
- Smoking Cessations ‐ Discontinuation of the habit of smoking, the inhaling and exhaling…
- Vertebro-Basilar Insufficiencies ‐ Localized or diffuse reduction in blood flow through the vertebrobasilar…
- Hyperbilirubinemia, Hereditary ‐ Inborn errors of bilirubin metabolism resulting in excessive…
- Partial Seizures, Vertiginous ‐ A disorder characterized by recurrent focal onset seizures which…
- Klebsiella mobilus ‐ Gram-negative, capsulated, gas-producing rods found widely in…
- Liner, Pants ‐ Absorbent pads made of various materials used for personal hygiene…
- Chemical Industries ‐ The aggregate enterprise of manufacturing and technically producing…
- Cytotoxic Brain Edema ‐ Increased intracellular or extracellular fluid in brain tissue.…
- Hormones, Thymic ‐ Humoral factors secreted by the thymus gland. They participate…