About The Medical Condition NSC-141540
Find the definition of the medical term NSC-141540. NSC-141540 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
NSC-141540
| NSC-141540 Medical Condition |
|---|
What's The Definition Of The Medical Condition NSC-141540?
A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Albumin Colloid, Technetium-99m ‐ A gamma-emitting radionuclide imaging agent used for the diagnosis…
- Plasmodium vivax ‐ A protozoan parasite that causes vivax malaria (MALARIA, VIVAX).…
- Calcium-Activated Potassium Channels ‐ Potassium channels whose activation is dependent on intracellular…
- Index, Human Reproductive ‐ The total process by which organisms produce offspring. (Stedman,…
- Aspartame ‐ Flavoring agent sweeter than sugar, metabolized as phenylalanine…
- Aneurysms, Cerebral ‐ Congenital or acquired abnormal outpouching of an intracranial…
- Levobunolol ‐ A nonselective beta-adrenoceptor antagonist used in the treatment…
- Protein, Myelin Proteolipid ‐ A myelin protein that is the major component of the organic solvent…
- AQL-208 ‐ An adrenergic beta-agonist used as a bronchodilator agent in…
- Thyronines ‐ A group of metabolites derived from THYROXINE and TRIIODOTHYRONINE…