About The Medical Condition Oncogene Protein gp140(v-fms)
Find the definition of the medical term Oncogene Protein gp140(v-fms). Oncogene Protein gp140(v-fms) defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Oncogene Protein gp140(v-fms)
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What's The Definition Of The Medical Condition Oncogene Protein gp140(v-fms)?
Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms).
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