About The Medical Condition Oncogene Protein HER-2

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Find the definition of the medical term Oncogene Protein HER-2. Oncogene Protein HER-2 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Oncogene Protein HER-2

Oncogene Protein HER-2 Medical Condition Defined & Explained
Oncogene Protein HER-2 Medical Condition

What's The Definition Of The Medical Condition Oncogene Protein HER-2?

A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR), the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members. EC 2.7.11.-.

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