About The Medical Condition Ophthalmoplegia, Progressive Supranuclear
Find the definition of the medical term Ophthalmoplegia, Progressive Supranuclear. Ophthalmoplegia, Progressive Supranuclear defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Ophthalmoplegia, Progressive Supranuclear
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What's The Definition Of The Medical Condition Ophthalmoplegia, Progressive Supranuclear?
A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)
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