About The Medical Condition Orthoclone OKT3
Find the definition of the medical term Orthoclone OKT3. Orthoclone OKT3 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Orthoclone OKT3
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What's The Definition Of The Medical Condition Orthoclone OKT3?
Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell depletion and modulation of the T-cell receptor complex (CD3/Ti). This biochemically purified IMMUNOGLOBULIN G is obtained through the fusion of mouse myeloma cells to lymphocytes from immunized animals to produce hybridomas that secrete specific antibodies to the T3 (CD3) antigens of human T-lymphocytes. It is often used as an immunosuppressive agent in transplantation.
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