About The Medical Condition Orthoclone OKT3

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Find the definition of the medical term Orthoclone OKT3. Orthoclone OKT3 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Orthoclone OKT3

Orthoclone OKT3 Medical Condition Defined & Explained
Orthoclone OKT3 Medical Condition

What's The Definition Of The Medical Condition Orthoclone OKT3?

Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell depletion and modulation of the T-cell receptor complex (CD3/Ti). This biochemically purified IMMUNOGLOBULIN G is obtained through the fusion of mouse myeloma cells to lymphocytes from immunized animals to produce hybridomas that secrete specific antibodies to the T3 (CD3) antigens of human T-lymphocytes. It is often used as an immunosuppressive agent in transplantation.

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