About The Medical Condition Parkinsonism, Primary
Find the definition of the medical term Parkinsonism, Primary. Parkinsonism, Primary defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Parkinsonism, Primary
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What's The Definition Of The Medical Condition Parkinsonism, Primary?
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
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