About The Medical Condition Pelizaeus-Merzbacher Diseases, Adult
Find the definition of the medical term Pelizaeus-Merzbacher Diseases, Adult. Pelizaeus-Merzbacher Diseases, Adult defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Pelizaeus-Merzbacher Diseases, Adult
Pelizaeus-Merzbacher Diseases, Adult Medical Condition |
---|
What's The Definition Of The Medical Condition Pelizaeus-Merzbacher Diseases, Adult?
A rare, slowly progressive disorder of myelin formation. Subtypes are referred to as classic, congenital, transitional, and adult forms of this disease. The classic form is X-chromosome linked, has its onset in infancy and is associated with a mutation of the proteolipid protein gene. Clinical manifestations include TREMOR, spasmus nutans, roving eye movements, ATAXIA, spasticity, and NYSTAGMUS. Death occurs by the third decade of life. The congenital form has similar characteristics but presents early in infancy and features rapid disease progression. Transitional and adult subtypes have a later onset and less severe symptomatology. Pathologic features include patchy areas of demyelination with preservation of perivascular islands (trigoid appearance). (From Menkes, Textbook of Child Neurology, 5th ed, p190)
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Verbal Behaviors ‐ Includes both producing and responding to words, either written…
- Hallucination, Gustatory ‐ Subjectively experienced sensations in the absence of an appropriate…
- Health Services, Urban ‐ Health services, public or private, in urban areas. The services…
- Cancer of the Cervix ‐ Tumors or cancer of the…
- Alpha-Chloralose ‐ A derivative of CHLORAL HYDRATE that was used as a sedative but…
- Service, Dental Health ‐ Services designed to promote, maintain, or restore…
- Labor ‐ The function in the female by which the product of conception…
- Insufficiency, Acute Renal ‐ A clinical syndrome characterized by a sudden decrease in glomerular…
- Sneezings ‐ Sudden, forceful, involuntary expulsion of air from the nose…
- Acid, Phosphotungstic ‐ Tungsten hydroxide oxide phosphate. A white or slightly yellowish-green,…