About The Medical Condition Periventricular Leukomalacia

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Find the definition of the medical term Periventricular Leukomalacia. Periventricular Leukomalacia defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Periventricular Leukomalacia

Periventricular Leukomalacia Medical Condition Defined & Explained
Periventricular Leukomalacia Medical Condition

What's The Definition Of The Medical Condition Periventricular Leukomalacia?

Degeneration of white matter adjacent to the CEREBRAL VENTRICLES following cerebral hypoxia or BRAIN ISCHEMIA in neonates. The condition primarily affects white matter in the perfusion zone between superficial and deep branches of the MIDDLE CEREBRAL ARTERY. Clinical manifestations include VISION DISORDERS; CEREBRAL PALSY; PARAPLEGIA; SEIZURES; and COGNITIVE DISORDERS. (From Adams et al., Principles of Neurology, 6th ed, p1021; Joynt, Clinical Neurology, 1997, Ch4, pp30-1)

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