About The Medical Condition Persistent Neonatal Myasthenia Gravis

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Find the definition of the medical term Persistent Neonatal Myasthenia Gravis. Persistent Neonatal Myasthenia Gravis defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Persistent Neonatal Myasthenia Gravis

Persistent Neonatal Myasthenia Gravis Medical Condition Defined & Explained
Persistent Neonatal Myasthenia Gravis Medical Condition

What's The Definition Of The Medical Condition Persistent Neonatal Myasthenia Gravis?

A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)

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