About The Medical Condition Phenacetin O-Dealkylase
Find the definition of the medical term Phenacetin O-Dealkylase. Phenacetin O-Dealkylase defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Phenacetin O-Dealkylase
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What's The Definition Of The Medical Condition Phenacetin O-Dealkylase?
A polycyclic aromatic hydrocarbon-inducible cytochrome which is of significant clinical interest due to the large number of drug interactions associated with induction and inhibition of theophylline. Caffeine is considered to be a model substrate for this enzyme. It also metabolizes theophylline and antipyrene. Environmental factors including cigarette smoking, charbroiled meat, cruciferous vegetables, and a number of drugs including phenytoin, phenobarbital, and omeprazole produce increases in CYP1A2 activity. (Ann Pharmacother 1995;29:619-24) EC 1.-.
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