About The Medical Condition Phosphofructokinase-1

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Find the definition of the medical term Phosphofructokinase-1. Phosphofructokinase-1 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Phosphofructokinase-1

Phosphofructokinase-1 Medical Condition Defined & Explained
Phosphofructokinase-1 Medical Condition

What's The Definition Of The Medical Condition Phosphofructokinase-1?

An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. D-tagatose- 6-phosphate and sedoheptulose-7-phosphate also are acceptors. UTP, CTP, and ITP also are donors. In human phosphofructokinase-1, three types of subunits have been identified. They are muscle type M (PHOSPHOFRUCTOKINASE-1, MUSCLE TYPE); liver type L (PHOSPHOFRUCTOKINASE-1, LIVER TYPE); and type C (PHOSPHOFRUCTOKINASE-1, C TYPE) found in platelets, brain, and other tissues.

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