About The Medical Condition Phosphofructokinase-2

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Find the definition of the medical term Phosphofructokinase-2. Phosphofructokinase-2 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Phosphofructokinase-2

Phosphofructokinase-2 Medical Condition Defined & Explained
Phosphofructokinase-2 Medical Condition

What's The Definition Of The Medical Condition Phosphofructokinase-2?

An allosteric enzyme that regulates glycolysis and gluconeogenesis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-2,6-bisphosphate, an allosteric effector for the other 6-phosphofructokinase, PHOSPHOFRUCTOKINASE-1. Phosphofructokinase-2 is bifunctional: the dephosphorylated form is a kinase and the phosphorylated form is a phosphatase that breaks down fructose-2,6-bisphosphate to yield fructose-6-phosphate.

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