About The Medical Condition Platelet Glycoprotein GPIb-IX Complex
Find the definition of the medical term Platelet Glycoprotein GPIb-IX Complex. Platelet Glycoprotein GPIb-IX Complex defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Platelet Glycoprotein GPIb-IX Complex
| Platelet Glycoprotein GPIb-IX Complex Medical Condition |
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What's The Definition Of The Medical Condition Platelet Glycoprotein GPIb-IX Complex?
Platelet membrane glycoprotein complex essential for normal platelet adhesion and clot formation at sites of vascular injury. It is composed of three polypeptides, GPIb alpha, GPIb beta, and GPIX. Glycoprotein Ib functions as a receptor for von Willebrand factor and for thrombin. Congenital deficiency of the GPIb-IX complex results in Bernard-Soulier syndrome. The platelet glycoprotein GPV associates with GPIb-IX and is also absent in Bernard-Soulier syndrome.
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