About The Medical Condition Platelet Transforming Growth Factor
Find the definition of the medical term Platelet Transforming Growth Factor. Platelet Transforming Growth Factor defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Platelet Transforming Growth Factor
| Platelet Transforming Growth Factor Medical Condition |
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What's The Definition Of The Medical Condition Platelet Transforming Growth Factor?
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
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