About The Medical Condition PP2B
Find the definition of the medical term PP2B. PP2B defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
PP2B
| PP2B Medical Condition |
|---|
What's The Definition Of The Medical Condition PP2B?
A calcium- and calmodulin-binding protein present in highest concentrations in the central nervous system. Calcineurin is composed of two subunits. A catalytic subunit, calcineurin A, and a regulatory subunit, calcineurin B, with molecular weights of about 60 kD and 19 kD, respectively. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including histones, myosin light chain, and the regulatory subunit of cAMP-dependent protein kinase. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes in T-lymphocytes that act by inhibiting T-cell activation. EC 3.1.3.-.
|
More Medical Conditions
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z
Medical Conditions Definitions Of The Day
- Care, Peroperative ‐ Patient care procedures performed during the operation that are…
- IgG2A ‐ The major immunoglobulin in normal…
- Intracranial Extradural Abscesses ‐ Circumscribed collections of suppurative material occurring in…
- Eczema, Atopic ‐ A chronic inflammatory genetically determined disease of the…
- Policy, Pronatalist ‐ A course or method of action selected, usually by a government,…
- Traumatic Myelopathy ‐ Penetrating and non-penetrating injuries to the spinal cord resulting…
- Anencephalias ‐ A malformation of the nervous system caused by failure of the…
- Chai Hu ‐ A plant genus of the family APIACEAE that is the source of bupleurum…
- Neurologic Disorder, Degenerative ‐ Hereditary and sporadic conditions which are characterized by…
- Ability ‐ The ability to acquire general or special types of knowledge…