About The Medical Condition Prions
Find the definition of the medical term Prions. Prions defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Prions
Prions Medical Condition |
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What's The Definition Of The Medical Condition Prions?
Small proteinaceous infectious particles which resist inactivation by procedures that modify nucleic acids and contain an abnormal isoform of a cellular protein which is a major and necessary component. The abnormal (scrapie) isoform is PrPSc (PRPSC PROTEINS) and the cellular isoform PrPC (PRPC PROTEINS). The primary amino acid sequence of the two isoforms is identical. Human diseases caused by prions include CREUTZFELDT-JAKOB SYNDROME and GERSTMANN-STRAUSSLER SYNDROME.
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