About The Medical Condition Probes, Chromosomal

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Find the definition of the medical term Probes, Chromosomal. Probes, Chromosomal defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Probes, Chromosomal

Probes, Chromosomal Medical Condition Defined & Explained
Probes, Chromosomal Medical Condition

What's The Definition Of The Medical Condition Probes, Chromosomal?

Species- or subspecies-specific DNA (including COMPLEMENTARY DNA; conserved genes, whole chromosomes, or whole genomes) used in hybridization studies in order to identify microorganisms, to measure DNA-DNA homologies, to group subspecies, etc. The DNA probe hybridizes with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, Southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the DNA probe include the radioisotope labels 32P and 125I and the chemical label biotin. The use of DNA probes provides a specific, sensitive, rapid, and inexpensive replacement for cell culture techniques for diagnosing infections.

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