About The Medical Condition Progressive Muscular Dystrophy, Duchenne Type
Find the definition of the medical term Progressive Muscular Dystrophy, Duchenne Type. Progressive Muscular Dystrophy, Duchenne Type defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Progressive Muscular Dystrophy, Duchenne Type
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What's The Definition Of The Medical Condition Progressive Muscular Dystrophy, Duchenne Type?
An X-linked recessive muscle disease caused by an inability to synthesize DYSTROPHIN, which is involved with maintaining the integrity of the sarcolemma. Muscle fibers undergo a process that features degeneration and regeneration. Clinical manifestations include proximal weakness in the first few years of life, pseudohypertrophy, cardiomyopathy (see MYOCARDIAL DISEASES), and an increased incidence of impaired mentation. Becker muscular dystrophy is a closely related condition featuring a later onset of disease (usually adolescence) and a slowly progressive course. (Adams et al., Principles of Neurology, 6th ed, p1415)
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