About The Medical Condition Progressive Supranuclear Palsies

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Find the definition of the medical term Progressive Supranuclear Palsies. Progressive Supranuclear Palsies defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Progressive Supranuclear Palsies

Progressive Supranuclear Palsies Medical Condition Defined & Explained
Progressive Supranuclear Palsies Medical Condition

What's The Definition Of The Medical Condition Progressive Supranuclear Palsies?

A degenerative disease of the central nervous system characterized by balance difficulties; OCULAR MOTILITY DISORDERS (supranuclear ophthalmoplegia); DYSARTHRIA; swallowing difficulties; and axial DYSTONIA. Onset is usually in the fifth decade and disease progression occurs over several years. Pathologic findings include neurofibrillary degeneration and neuronal loss in the dorsal MESENCEPHALON; SUBTHALAMIC NUCLEUS; RED NUCLEUS; pallidum; dentate nucleus; and vestibular nuclei. (From Adams et al., Principles of Neurology, 6th ed, pp1076-7)

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