About The Medical Condition Protein 1, IGF-Binding
Find the definition of the medical term Protein 1, IGF-Binding. Protein 1, IGF-Binding defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Protein 1, IGF-Binding
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What's The Definition Of The Medical Condition Protein 1, IGF-Binding?
One of the six homologous proteins that specifically bind insulin-like growth factors (SOMATOMEDINS) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits IGF binding to cell surface receptors and thereby inhibits IGF-mediated mitogenic and cell metabolic actions. (Proc Soc Exp Biol Med 1993;204(1):4-29)
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