About The Medical Condition Protein Receptor, Cell-Adhesion
Find the definition of the medical term Protein Receptor, Cell-Adhesion. Protein Receptor, Cell-Adhesion defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Protein Receptor, Cell-Adhesion
| Protein Receptor, Cell-Adhesion Medical Condition |
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What's The Definition Of The Medical Condition Protein Receptor, Cell-Adhesion?
A family of transmembrane glycoproteins consisting of noncovalent heterodimers. They interact with a wide variety of ligands including extracellular matrix glycoproteins, complement, and other cells, while their intracellular domains interact with the cytoskeleton. The integrins consist of at least three identified families: the cytoadhesin receptors, the leukocyte adhesion receptors, and the very-late-antigen receptors. Each family contains a common beta-subunit combined with one or more distinct alpha-subunits. These receptors participate in cell-matrix and cell-cell adhesion in many physiologically important processes, including embryological development, hemostasis, thrombosis, wound healing, immune and nonimmune defense mechanisms, and oncogenic transformation.
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