About The Medical Condition Proteins, bcr-abl Fusion
Find the definition of the medical term Proteins, bcr-abl Fusion. Proteins, bcr-abl Fusion defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Proteins, bcr-abl Fusion
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What's The Definition Of The Medical Condition Proteins, bcr-abl Fusion?
Translation products of a fusion mRNA derived from the breakpoint cluster region (bcr) gene and a cellular abl (c-abl) gene translocated to chromosome 22. The p210(bcr-abl) fusion protein is found in patients with chronic myelogenous leukemia. The p190(bcr-abl) fusion protein is found in patients with acute lymphocytic leukemia. The activation of human c-abl by chromosomal translocation is essentially the same as the activation of murine c-abl by viral translocation in Abelson murine leukemia virus.
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