About The Medical Condition Proto-Oncogene, bcr-abl
Find the definition of the medical term Proto-Oncogene, bcr-abl. Proto-Oncogene, bcr-abl defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Proto-Oncogene, bcr-abl
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What's The Definition Of The Medical Condition Proto-Oncogene, bcr-abl?
Retrovirus-associated DNA sequences (abl) originally isolated from the Abelson murine leukemia virus (Ab-MuLV). The proto-oncogene abl (c-abl) codes for a protein that is a member of the tyrosine kinase family. The human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It is activated by translocation to bcr on chromosome 22 in chronic myelogenous leukemia.
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