About The Medical Condition Proto-Oncogene Products, erbA

ClusterMed

Find the definition of the medical term Proto-Oncogene Products, erbA. Proto-Oncogene Products, erbA defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Proto-Oncogene Products, erbA

Proto-Oncogene Products, erbA Medical Condition Defined & Explained
Proto-Oncogene Products, erbA Medical Condition

What's The Definition Of The Medical Condition Proto-Oncogene Products, erbA?

Proteins, usually found in the nucleus, that specifically bind thyroid hormones and regulate DNA transcription. These proteins, termed c-erbA, are activated by hormones and cause differentiation of erythroid progenitor cells which irreversibly lose proliferative potential. Thus c-erbA proteins act as growth suppressors. The c-erbA proteins are encoded by at least two genes, c-erbA alpha and c-erbA beta. Each of these has two isoforms. Mutations in the ligand-binding domain of the beta form causes THYROID HORMONE RESISTANCE SYNDROME.

More Medical Conditions

A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z

Medical Conditions Definitions Of The Day