About The Medical Condition Proto-Oncogene Protein c-met
Find the definition of the medical term Proto-Oncogene Protein c-met. Proto-Oncogene Protein c-met defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Proto-Oncogene Protein c-met
| Proto-Oncogene Protein c-met Medical Condition |
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What's The Definition Of The Medical Condition Proto-Oncogene Protein c-met?
A cell surface protein-tyrosine kinase receptor for HEPATOCYTE GROWTH FACTOR. It consists of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and critical sites for the regulation of kinase activity. Mutations of the gene for PROTO-ONCOGENE PROTEIN C-MET are associated with papillary renal carcinoma and other neoplasia. EC 2.7.11.-.
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