About The Medical Condition Proto-Oncogene Protein, erbB-1
Find the definition of the medical term Proto-Oncogene Protein, erbB-1. Proto-Oncogene Protein, erbB-1 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Proto-Oncogene Protein, erbB-1
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What's The Definition Of The Medical Condition Proto-Oncogene Protein, erbB-1?
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF related peptides including TRANSFORMING GROWTH FACTOR ALPHA, amphiregulin, and heparin-binding EGF-like growth factor. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell. EC 2.7.11.-.
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