About The Medical Condition Proto-Oncogene Protein, HER-3
Find the definition of the medical term Proto-Oncogene Protein, HER-3. Proto-Oncogene Protein, HER-3 defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Proto-Oncogene Protein, HER-3
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What's The Definition Of The Medical Condition Proto-Oncogene Protein, HER-3?
A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF Receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR) and the erbB-2 receptor (RECEPTOR, ERBB-2). Overexpression of the erbB-3 receptor is associated with tumorigenesis. EC 2.7.11.-.
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