About The Medical Condition Proto-Oncogene Proteins c-kit
Find the definition of the medical term Proto-Oncogene Proteins c-kit. Proto-Oncogene Proteins c-kit defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Proto-Oncogene Proteins c-kit
| Proto-Oncogene Proteins c-kit Medical Condition |
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What's The Definition Of The Medical Condition Proto-Oncogene Proteins c-kit?
A protein-tyrosine kinase receptor that is specific for STEM CELL FACTOR. This interaction is crucial for the development of hematopoietic, gonadal, and pigment stem cells. Genetic mutations that disrupt the expression of PROTO-ONCOGENE PROTEIN C-KIT are associated with PIEBALDISM, while overexpression or constitutive activation of the c-kit protein-tyrosine kinase is associated with tumorigenesis. EC 2.7.11.-.
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