About The Medical Condition Proto-Oncogene Proteins c-rel

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Find the definition of the medical term Proto-Oncogene Proteins c-rel. Proto-Oncogene Proteins c-rel defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Proto-Oncogene Proteins c-rel

Proto-Oncogene Proteins c-rel Medical Condition Defined & Explained
Proto-Oncogene Proteins c-rel Medical Condition

What's The Definition Of The Medical Condition Proto-Oncogene Proteins c-rel?

Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.

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