About The Medical Condition Proto-Oncogenes, c-myc
Find the definition of the medical term Proto-Oncogenes, c-myc. Proto-Oncogenes, c-myc defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Proto-Oncogenes, c-myc
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What's The Definition Of The Medical Condition Proto-Oncogenes, c-myc?
Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.
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