About The Medical Condition Rb Gene

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Find the definition of the medical term Rb Gene. Rb Gene defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Rb Gene

Rb Gene Medical Condition Defined & Explained
Rb Gene Medical Condition

What's The Definition Of The Medical Condition Rb Gene?

Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.

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