About The Medical Condition Receptor, erbB-2

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Receptor, erbB-2

Receptor, erbB-2 Medical Condition Defined & Explained
Receptor, erbB-2 Medical Condition

What's The Definition Of The Medical Condition Receptor, erbB-2?

A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR), the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members. EC 2.7.11.-.

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