About The Medical Condition Receptor Family, Leu-CAM
Find the definition of the medical term Receptor Family, Leu-CAM. Receptor Family, Leu-CAM defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Receptor Family, Leu-CAM
| Receptor Family, Leu-CAM Medical Condition |
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What's The Definition Of The Medical Condition Receptor Family, Leu-CAM?
Family of proteins associated with the capacity of leukocytes, including lymphocytes, monocytes, and neutrophils, to adhere to each other and to certain substrata, e.g., the C3bi component of complement. Members of this family are the LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; (LFA-1), the MACROPHAGE-1 ANTIGEN; (Mac-1), and the COMPLEMENT 4-BINDING PROTEIN or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited LEUKOCYTE-ADHESION DEFICIENCY SYNDROME, which is characterized by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells.
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