About The Medical Condition Receptor, IGF-I
Find the definition of the medical term Receptor, IGF-I. Receptor, IGF-I defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Receptor, IGF-I
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What's The Definition Of The Medical Condition Receptor, IGF-I?
A protein-tyrosine kinase receptor that is closely related in structure to the INSULIN RECEPTOR. Although commonly referred to as the IGF-I receptor, it binds both IGF-I and IGF-II with high affinity. It is comprised of a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precusor protein. The beta subunit contains an intrisic tyrosine kinase domain. EC 2.7.11.-.
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