About The Medical Condition Receptor, TCGF
Find the definition of the medical term Receptor, TCGF. Receptor, TCGF defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Receptor, TCGF
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What's The Definition Of The Medical Condition Receptor, TCGF?
Receptors present on activated T- and B-cells as a complex consisting of a 55 kD peptide, which reacts with the anti-Tac monoclonal antibody, and a 75 kD non-Tac interleukin-2-binding peptide. The receptor is present in two forms, one with a very high affinity and the other with low affinity for IL-2. The high-affinity form appears to mediate exclusively the growth-promoting response to IL-2. The receptor is present in large numbers on resting HUMAN T-LYMPHOTROPIC VIRUS 1 leukemia cells, but not on normal resting cells.
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