About The Medical Condition Receptors, Baclofen
Find the definition of the medical term Receptors, Baclofen. Receptors, Baclofen defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Receptors, Baclofen
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What's The Definition Of The Medical Condition Receptors, Baclofen?
Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and influence cells via interactions with G-proteins. GABA-B receptors are pharmacologically characterized by their insensitivity to the blocker bicuculline and sensitivity to the agonist L-baclofen. They are found both presynaptically and postsynaptically, and act variously by inhibition of adenylate cyclase, activation of phospholipase A2, activation of potassium channels, and inactivation of voltage-activated calcium channels.
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