About The Medical Condition Receptors, GABA-B
Find the definition of the medical term Receptors, GABA-B. Receptors, GABA-B defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Receptors, GABA-B
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What's The Definition Of The Medical Condition Receptors, GABA-B?
Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and influence cells via interactions with G-proteins. GABA-B receptors are pharmacologically characterized by their insensitivity to the blocker bicuculline and sensitivity to the agonist L-baclofen. They are found both presynaptically and postsynaptically, and act variously by inhibition of adenylate cyclase, activation of phospholipase A2, activation of potassium channels, and inactivation of voltage-activated calcium channels.
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