About The Medical Condition Receptors, N-Methylaspartate
Find the definition of the medical term Receptors, N-Methylaspartate. Receptors, N-Methylaspartate defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Receptors, N-Methylaspartate
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What's The Definition Of The Medical Condition Receptors, N-Methylaspartate?
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity.
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