About The Medical Condition Recording, Whole-Cell
Find the definition of the medical term Recording, Whole-Cell. Recording, Whole-Cell defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.
Recording, Whole-Cell
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What's The Definition Of The Medical Condition Recording, Whole-Cell?
An electrophysiologic technique for studying cells, cell membranes, and occasionally isolated organelles. All patch-clamp methods rely on a very high-resistance seal between a micropipette and a membrane; the seal is usually attained by gentle suction. The four most common variants include on-cell patch, inside-out patch, outside-out patch, and whole-cell clamp. Patch-clamp methods are commonly used to voltage clamp, that is control the voltage across the membrane and measure current flow, but current-clamp methods, in which the current is controlled and the voltage is measured, are also used.
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