About The Medical Condition Rel Proto-Oncogene Proteins

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Find the definition of the medical term Rel Proto-Oncogene Proteins. Rel Proto-Oncogene Proteins defined and explained for easy understanding at the Medical Conditions from ClusterMed.info.

Rel Proto-Oncogene Proteins

Rel Proto-Oncogene Proteins Medical Condition Defined & Explained
Rel Proto-Oncogene Proteins Medical Condition

What's The Definition Of The Medical Condition Rel Proto-Oncogene Proteins?

Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.

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